Below you can find all the papers associated to Prof. Lorenzo-Luaces. Not all these papers were written primarily while I was at Indiana University but they are all representative of the interests of the lab. Some of these papers were written while I was at the University of Pennsylvania or by colleagues in Amsterdam or Spain!

1. Vélez, Y. D., Lorenzo-Luaces, L., & Rosselló, J. (2012). Ideación suicida: Sı́ntomas depresivos, pensamientos disfuncionales, autoconcepto, y estrategias de manejo en adolescentes puertorriqueños. Revista Puertorriqueña de Psicologı́a, 23(2), 1.
2. Lorenzo-Luaces, L., & Phillips, J. A. (2014). Racial and ethnic differences in risk factors associated with suicidal behavior among young adults in the USA. Ethnicity & Health, 19(4), 458–477.
3. DeRubeis, R. J., Cohen, Z. D., Forand, N. R., Fournier, J. C., Gelfand, L. A., & Lorenzo-Luaces, L. (2014). The Personalized Advantage Index: Translating research on prediction into individualized treatment recommendations. A demonstration. PLOS ONE, 9(1), e83875.
4. Lorenzo-Luaces, L., DeRubeis, R. J., & Webb, C. A. (2014). Client characteristics as moderators of the relation between the therapeutic alliance and outcome in cognitive therapy for depression. Journal of Consulting and Clinical Psychology, 82(2), 368.
5. German, R. E., Lorenzo-Luaces, L., & DeRubeis, R. J. (2014). Patient’s attributions about symptom improvement in CBT for depression: Development of a rating system and an initial test of validity. International Journal of Cognitive Therapy, 7(3), 272–286.
6. Lorenzo-Luaces, L., German, R. E., & DeRubeis, R. J. (2015). It’s complicated: The relation between cognitive change procedures, cognitive change, and symptom change in cognitive therapy for depression. Clinical Psychology Review, 41, 3–15.
7. Lorenzo-Luaces, L. (2015). Heterogeneity in the prognosis of major depression: From the common cold to a highly debilitating and recurrent illness. Epidemiology and Psychiatric Sciences.
8. Lorenzo-Luaces, L., DeRubeis, R. J., & Bennett, I. M. (2015). Primary care physician’s selection of low-intensity treatments for patients with depression. Family Medicine, 47(7), 511–516.
9. Amsterdam, J. D., Lorenzo-Luaces, L., Soeller, I., Li, S. Q., Mao, J. J., & DeRubeis, R. J. (2015). Safety and effectiveness of continuation antidepressant versus mood stabilizer monotherapy for relapse-prevention of bipolar II depression: A randomized, double-blind, parallel-group, prospective study. Journal of Affective Disorders, 185, 31–37.
10. Lorenzo-Luaces, L., Amsterdam, J. D., Soeller, I., & DeRubeis, R. J. (2016). Rapid versus non-rapid cycling bipolar II depression: Response to venlafaxine and lithium and hypomanic risk. Acta Psychiatrica Scandinavica, 133(6), 459–469.
11. Amsterdam, J. D., Lorenzo-Luaces, L., Soeller, I., Li, S. Q., Mao, J. J., & DeRubeis, R. J. (2016). Short-term venlafaxine versus lithium monotherapy for bipolar type II major depressive episodes: Effectiveness and mood conversion rate. The British Journal of Psychiatry, 208(4), 359–365.
12. Lorenzo-Luaces, L., Keefe, J. R., & DeRubeis, R. J. (2016). Cognitive-behavioral therapy: Nature and relation to non-cognitive behavioral therapy. Behavior Therapy, 47(6), 785–803.
13. DeRubeis, R. J., Strunk, D. R., & Lorenzo-Luaces, L. (2016). Mood disorders.
14. Horwitz, A. V., Wakefield, J. C., & Lorenzo-Luaces, L. (2016). History of depression. The Oxford Handbook of Mood Disorders, 11–23.
15. Amsterdam, J. D., Lorenzo-Luaces, L., & DeRubeis, R. J. (2016). Step-wise loss of antidepressant effectiveness with repeated antidepressant trials in bipolar II depression. Bipolar Disorders, 18(7), 563–570.
16. Lorenzo-Luaces, L., Driessen, E., DeRubeis, R. J., Van, H. L., Keefe, J. R., Hendriksen, M., & Dekker, J. (2017). Moderation of the alliance-outcome association by prior depressive episodes: Differential effects in cognitive-behavioral therapy and short-term psychodynamic supportive psychotherapy. Behavior Therapy, 48(5), 581–595.
17. DeRubeis, R. J., & Lorenzo-Luaces, L. (2017). Recognizing that truth is unattainable and attending to the most informative research evidence. Psychotherapy Research, 27(1), 33–35.
18. Amsterdam, J. D., Lorenzo-Luaces, L., & DeRubeis, R. J. (2017). Comparison of treatment outcome using two definitions of rapid cycling in subjects with bipolar II disorder. Bipolar Disorders, 19(1), 6–12.
19. Lorenzo-Luaces, L., DeRubeis, R. J., Straten, A. van, & Tiemens, B. (2017). A prognostic index (PI as a moderator of outcomes in the treatment of depression: A proof of concept combining multiple variables to inform risk-stratified stepped care models. Journal of Affective Disorders, 213, 78–85.
20. Amsterdam, J., Lorenzo-Luaces, L., & DeRubeis, R. (2017). Step-wise loss of antidepressant effectiveness with repeated antidepressant trials in bipolar II depression. Bipolar Disorders, 19, 17–17.
21. Wakefield, J. C., Lorenzo-Luaces, L., & Lee, J. J. (2017). Taking people as they are: Evolutionary psychopathology, uncomplicated depression, and distinction between normal and disordered sadness. In The evolution of psychopathology (pp. 37–72). Springer, Cham.
22. Lorenzo-Luaces, L., Amsterdam, J. D., & DeRubeis, R. J. (2018). Residual anxiety may be associated with depressive relapse during continuation therapy of bipolar II depression. Journal of Affective Disorders, 227, 379–383.
23. Lorenzo-Luaces, L., & Amsterdam, J. D. (2018). Effects of venlafaxine versus lithium monotherapy on quality of life in bipolar II major depressive disorder: Findings from a double-blind randomized controlled trial. Psychiatry Research, 259, 455–459.
24. Lorenzo-Luaces, L., & DeRubeis, R. J. (2018). Miles to go before we sleep: Advancing the understanding of psychotherapy by modeling complex processes. Cognitive Therapy and Research, 42(2), 212–217.
25. Lorenzo-Luaces, L. (2018). The evidence for cognitive behavioral therapy. JAMA, 319(8), 831–832.
26. Lorenzo-Luaces, L., Zimmerman, M., & Cuijpers, P. (2018). Are studies of psychotherapies for depression more or less generalizable than studies of antidepressants? Journal of Affective Disorders, 234, 8–13.
27. Lorenzo-Luaces, L. (2018). Representing the heterogeneity of depression in treatment research. Acta Psychiatrica Scandinavica, 138(4), 360–361.
28. Lorenzo-Luaces, L., Johns, E., Keefe, J. R., et al. (2018). The generalizability of randomized controlled trials of self-guided internet-based cognitive behavioral therapy for depressive symptoms: Systematic review and meta-regression analysis. Journal of Medical Internet Research, 20(11), e10113.
29. Amsterdam, J. D., & Lorenzo-Luaces, L. (2018). Wzrost tolerancji farmakodynamicznej po wielokrotnym leczeniu lekami antydepresyjnymi pacjentów z chorobą afektywną dwubiegunową typu II podatną na leczenie. Badanie eksploracyjne. Psychiatr. Polska, 52(6), 957–969.
30. Amsterdam, J. D., & Lorenzo-Luaces, L. (2019). An extrapolation model? Bipolar II Disorder: Modelling, Measuring and Managing, 213.
31. Lorenzo-Luaces, L., & Dobson, K. S. (2019). Is behavioral activation (BA) more effective than cognitive therapy (CT) in severe depression? A reanalysis of a landmark trial. International Journal of Cognitive Therapy, 12(2), 73–82.
32. Lopez-Gomez, I., Lorenzo-Luaces, L., Chaves, C., Hervas, G., DeRubeis, R. J., & Vazquez, C. (2019). Predicting optimal interventions for clinical depression: Moderators of outcomes in a positive psychological intervention vs. Cognitive-behavioral therapy. General Hospital Psychiatry, 61, 104–110.
33. Buss, J., Lorenzo-Luaces, L., Banks, G., Horani, D., Rutter, L., & Wasil, A. R. (2020). Availability of internet-based cognitive behavioral therapies (iCBTs) for depression: A systematic review.
34. Lorenzo-Luaces, L., Rodriguez-Quintana, N., Riley, T. N., & Weisz, J. R. (2021). A placebo prognostic index (PI) as a moderator of outcomes in the treatment of adolescent depression: Could it inform risk-stratification in treatment with cognitive-behavioral therapy, fluoxetine, or their combination? Psychotherapy Research, 31(1), 5–18.
35. Lorenzo-Luaces, L., Rodriguez-Quintana, N., & Bailey, A. J. (2020). Double trouble: Do symptom severity and duration interact to predicting treatment outcomes in adolescent depression? Behaviour Research and Therapy, 131, 103637.
36. Fried, E. I., Coomans, F., & Lorenzo-Luaces, L. (2020). The 341,737 ways of qualifying for the melancholic specifier. The Lancet Psychiatry, 7(6), 479–480.
37. Wakefield, J. C., Horwitz, A. V., & Lorenzo-Luaces, L. (2016). Uncomplicated depression as normal sadness. The Oxford Handbook of Mood Disorders.
38. Fried, E. I., & Lorenzo-Luaces, L. (2020). Operationalism and its discontents–authors’ reply. The Lancet Psychiatry, 7(8), 666–667.
39. Howard, J., De Jesús-Romero, R., Peipert, A., Riley, T., Rutter, L. A., & Lorenzo-Luaces, L. (2021). The significance of anxiety symptoms in predicting psychosocial functioning across borderline personality traits. PLOS ONE, 16(1), e0245099.
40. Lorenzo-Luaces, L., Rutter, L. A., & Scalco, M. D. (2020). Carving depression at its joints? Psychometric properties of the Sydney Melancholia Prototype Index. Psychiatry Research, 293, 113410.
41. Wasil, A. R., Malhotra, T., Tuteja, N., Nandakumar, N., Pandole, L., DeRubeis, R., Lorenzo-Luaces, L., Naslund, J., & Bhatia, A. (2020). Preferences toward digital and non-digital mental health treatment delivery formats: A survey of indian college students.
42. Van Bronswijk, S. C., Bruijniks, S. J., Lorenzo-Luaces, L., Derubeis, R. J., Lemmens, L. H., Peeters, F. P., & Huibers, M. J. (2021). Cross-trial prediction in psychotherapy: External validation of the Personalized Advantage Index using machine learning in two Dutch randomized trials comparing CBT versus IPT for depression. Psychotherapy Research, 31(1), 78–91.
43. Lorenzo-Luaces, L., Wiedemann, M., Huibers, M. J., & Lemmens, L. H. (2020). A permutation test to probe the statistical significance of sudden gain frequency: An application to patterns of change in cognitive and interpersonal therapy for depression.
44. Ten Thij, M., Bathina, K., Rutter, L. A., Lorenzo-Luaces, L., Leemput, I. A. van de, Scheffer, M., & Bollen, J. (2020). Depression alters the circadian pattern of online activity. Scientific Reports, 10(1), 1–10.
45. Lorenzo-Luaces, L., Peipert, A., De Jesús Romero, R., Rutter, L. A., & Rodriguez-Quintana, N. (2021). Personalized medicine and cognitive behavioral therapies for depression: Small effects, big problems, and bigger data. International Journal of Cognitive Therapy, 14(1), 59–85.
46. Huibers, M. J., Lorenzo-Luaces, L., Cuijpers, P., & Kazantzis, N. (2021). On the road to personalized psychotherapy: A research agenda based on cognitive behavior therapy for depression. Frontiers in Psychiatry, 11, 1551.
47. Wasil, A. R., Gillespie, S., Schell, T., Lorenzo-Luaces, L., & DeRubeis, R. J. (2021). Estimating the real-world usage of mobile apps for mental health: Development and application of two novel metrics. World Psychiatry, 20(1), 137.
48. Bathina, K. C., Ten Thij, M., Lorenzo-Luaces, L., Rutter, L. A., & Bollen, J. (2021). Individuals with depression express more distorted thinking on social media. Nature Human Behaviour, 5(4), 458–466.
49. Lorenzo-Luaces, L., Lemmens, L. H., Keefe, J. R., Cuijpers, P., & Bockting, C. L. (2021). The efficacy of cognitive behavioral therapy for emotional disorders.
50. Bollen, J., Ten Thij, M., Breithaupt, F., Barron, A. T., Rutter, L. A., Lorenzo-Luaces, L., & Scheffer, M. (2021). Historical language records reveal a surge of cognitive distortions in recent decades. Proceedings of the National Academy of Sciences, 118(30).
51. Strunk, D. R., Lorenzo-Luaces, L., Huibers, M. J., & Kazantzis, N. (2021). Contemporary issues in defining the mechanisms of cognitive behavior therapy. Frontiers in Psychiatry, 1541.
52. Rutter, L. A., Thompson, H. M., Howard, J., Riley, T. N., De Jesús-Romero, R., & Lorenzo-Luaces, L. (2021). Social media use, physical activity, and internalizing symptoms in adolescence: Cross-sectional analysis. JMIR Mental Health, 8(9), e26134.
53. Lorenzo-Luaces, L., Buss, J. F., & Fried, E. I. (2021). Heterogeneity in major depression and its melancholic and atypical specifiers: A secondary analysis of STAR* d. BMC Psychiatry, 21(1), 1–11.
54. Bollen, J., Ten Thij, M., Breithaupt, F., Barron, A. T., Rutter, L. A., Lorenzo-Luaces, L., & Scheffer, M. (2021). Reply to Schmidt et al.: A robust surge of cognitive distortions in historical language. Proceedings of the National Academy of Sciences, 118(45).
55. Lorenzo-Luaces, L. (2022). Wider, faster, more: Re-envisioning the treatment and research of depression to address its public health burden in the United States.
56. Krendl, A. C., & Lorenzo-Luaces, L. (2022). Identifying peaks in attrition after clients initiate mental health treatment in a university training clinic. Psychological Services, 19(3), 519.
57. Wasil, A. R., Palermo, E. H., Lorenzo-Luaces, L., & DeRubeis, R. J. (2022). Is there an app for that? A review of popular apps for depression, anxiety, and well-being. Cognitive and Behavioral Practice, 29(4), 883–901.
58. Buss, J. F., Rutter, L. A., Howard, J., & Lorenzo-Luaces, L. (2022). The road to cognitive skill acquisition: Psychometric evaluation of the Competencies of Cognitive Therapy Scale. American Journal of Psychotherapy, 75(2), 75–81.
59. Lorenzo-Luaces, L., Howard, J., De Jesús-Romero, R., Peipert, A., Buss, J. F., Lind, C., Botts, K., & Starvaggi, I. (2023). Acceptability and outcomes of transdiagnostic guided self-help bibliotherapy for internalizing disorder symptoms in adults: A fully remote nationwide open trial. Cognitive Therapy and Research, 47(2), 195–208.
60. Peipert, A., Rodriguez-Quintana, N., & Lorenzo-Luaces, L. (2022). Outcomes of student trainee-delivered cognitive behavioral therapy (CBT) on internalizing symptoms, CBT skills, and life satisfaction. International Journal of Cognitive Therapy, 15(1), 94–113.
61. Lorenzo-Luaces, L. (2022). Identifying active ingredients in cognitive-behavioral therapies: What if we didn’t?(or couldn’t?).
62. Peipert, A., Adams, S., & Lorenzo-Luaces, L. (2022). Heterogeneity in item content of quality of life assessments used in depression research.
63. Wasil, A. R., Kacmarek, C., DeRubeis, R. J., & Lorenzo-Luaces, L. (2022). Race and socioeconomic status as predictors of willingness to use internet-based treatments or face-to-face psychotherapy: A nationally representative study.
64. De Jesús-Romero, R., Holder-Dixon, A., & Lorenzo-Luaces, L. (2022). Reporting and representation of racial and ethnic diversity in randomized controlled trials of internet-based cognitive-behavioral therapy (iCBT) for depression.
65. Driessen, E., Cohen, Z. D., Lorenzo-Luaces, L., Hollon, S. D., Richards, D. A., Dobson, K. S., Dimidjian, S., Delgadillo, J., Vázquez, F. L., McNamara, K., et al. (2022). Efficacy and moderators of cognitive therapy versus behavioural activation for adults with depression: Study protocol of a systematic review and meta-analysis of individual participant data. BJPsych Open, 8(5), e154.
66. Bronswijk, S. C. van, Howard, J., & Lorenzo-Luaces, L. (2022). Data-driven personalized medicine approaches to cognitive-behavioral therapy allocation in a large sample: A reanalysis of the ENRICHED study.
67. De Jesús-Romero, R., Wasil, A., Lorenzo-Luaces, L., et al. (2022). Willingness to use internet-based versus bibliotherapy interventions in a representative US sample: Cross-sectional survey study. JMIR Formative Research, 6(8), e39508.
68. Scalco, M. D., Lorenzo-Luaces, L., Evans, M., Sloss, A., Read, J. P., & Colder, C. R. (2022). Conceptualization of alcohol use disorder (AUD): Can theoretical or data driven approaches improve the construct validity of AUD? Research on Child and Adolescent Psychopathology, 50(12), 1605–1618.
69. Peipert, A., Krendl, A. C., Lorenzo-Luaces, L., et al. (2022). Waiting lists for psychotherapy and provider attitudes toward low-intensity treatments as potential interventions: Survey study. JMIR Formative Research, 6(9), e39787.
70. Bollen, J., Thij, M. ten, Lorenzo-Luaces, L., & Rutter, L. A. (2022). Beyond risk: Individual mental health trajectories from large-scale social media data. In Early detection of mental health disorders by social media monitoring: The first five years of the eRisk project (pp. 265–287). Springer International Publishing Cham.
71. Lorenzo-Luaces, L., Howard, J., Edinger, A., Yan, H. Y., Rutter, L. A., Valdez, D., Bollen, J., et al. (2022). Sociodemographics and transdiagnostic mental health symptoms in SOCIAL (studies of online cohorts for internalizing symptoms and language) i and II: Cross-sectional survey and botometer analysis. JMIR Formative Research, 6(10), e39324.
72. De Jesús-Romero, R., Starvaggi, I., Howard, J., Peipert, A., Buss, J., Lind, C. M., Riley, T. N., & Lorenzo-Luaces, L. (2022). Emotion regulation as a mechanism of change in transdiagnostic low-intensity cognitive behavioral therapy for internalizing distress: Disaggregating within vs. Between individual.
73. Lorenzo-Luaces, L., & Howard, J. (2022). Efficacy of a single session intervention for depression in online workers: A randomized controlled trial with transdiagnostic mental health outcomes.
74. Riley, T. N., Thompson, H. M., Howard, J., Lorenzo-Luaces, L., & Rutter, L. A. (2022). Seeking connectedness through social media use: Associations with adolescent empathic understanding and perspective-taking. Current Psychology, 1–13.
75. Rutter, L. A., Howard, J., Lakhan, P., Valdez, D., Bollen, J., & Lorenzo-Luaces, L. (2023). “I haven’t been diagnosed, but i should be”—insight into self-diagnoses of common mental health disorders: Cross-sectional study. JMIR Formative Research, 7(1), e39206.
76. Buss, J. F., Watts, A. L., & Lorenzo-Luaces, L. (2023). Information theory methods for quantifying diagnostic heterogeneity in psychopathology.
77. Lorenzo-Luaces, L., Rutter, L., Howard, J., Boinpally, M., Valdez, D., & Bollen, J. (2023). Using natural language processing to understand changes in emotions and psychopathology: Evidence from observational cohorts and a clinical trial.
78. Lorenzo-Luaces, L., Dierckman, C., & Adams, S. (2023). Attitudes and (mis) information about cognitive behavioral therapy on TikTok: An analysis of video content. Journal of Medical Internet Research, 25, e45571.
79. Peipert, A., Adams, S., & Lorenzo-Luaces, L. (2023). 213 provider-identified barriers to recommending low-intensity treatments for patients awaiting mental health care. Journal of Clinical and Translational Science, 7(s1), 65–65.
80. Edinger, A., Valdez, D., Walsh-Buhi, E., Trueblood, J. S., Lorenzo-Luaces, L., Rutter, L. A., & Bollen, J. (2023). Misinformation and public health messaging in the early stages of the mpox outbreak: Mapping the twitter narrative with deep learning. Journal of Medical Internet Research, 25, e43841.
81. Peipert, A., Adams, S., & Lorenzo-Luaces, L. (2023). “I would not want the mechanic to direct me to an engine repair manual”: A qualitative analysis of provider perspectives on low-intensity treatments for patients on waiting lists. Pre-Print Submitted for Publication.
82. Last, B. S., Wuest, J., Grey, M., Rivera, D. P., Rodriguez-Seijas, C. A., & Lorenzo-Luaces, L. (2023). Reply to rosik, beckstead, & lefevor (2023),“sexual orientation change efforts: Health associations, sexual identity labeling, and reports of change by engagement status”.